Syringe Filters, 13mm, Nylon, 0.45um Pore Size. Green Polypropylene, AQ Brand. 50/PK.

Additional Info:

The 58045-N13-A AQ™ Syringe Filters are pharmaceutical-grade, high-performance membrane filters engineered for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm Nylon‑66 membrane, these filters deliver exceptional consistency, ultra-low adsorption, and extractable-free performance, ensuring accurate and reproducible analytical results for critical workflows.

The 13 mm format is optimized for low sample volume applications, providing efficient filtration while minimizing sample loss. Designed for high-performance use, these filters are an excellent choice when chromatographic reliability and consistency cannot be compromised.


✅ Critical Compliance Advantage (No Flush Required)

These filters are validated and certified to meet stringent regulatory requirements, including:

  • US FDA CFR Title 21, Part 210.3(b)(6) for minimum fiber release

  • USP <788> for particulate matter in injectables

  • USP requirements for “Sterile Water for Injection”

Because of this validated performance:

  • ✅ No initial flushing is required

  • ✅ No need to discard the first 200 µL of filtrate

  • ✅ Preserves valuable sample—even in low-volume workflows

  • ✅ Saves time and reduces risk of failed methods and investigations

👉 This is a critical advantage for QC/QA laboratories, especially when working with limited or high-value samples, where sample conservation and compliance are essential.


Performance & Design

The 0.45 µm pore size is ideal for sample clarification and prefiltration, delivering high flow rates with reduced clogging, improving efficiency in routine analytical work.

Nylon‑66 membrane chemistry ensures broad compatibility with aqueous and organic HPLC solvents, while maintaining ultra-low adsorption—even for charged analytes, supporting accurate quantitation.

Unlike larger formats, the 13 mm filter is designed for small sample volumes, with minimal hold-up and reduced waste, making it well suited for analytical labs and method development.

The green color coding allows immediate identification of 0.45 µm nylon filters, and each pack includes a Certificate of Analysis for full traceability and compliance.


Key Features

0.45 µm Nylon‑66 Membrane (Pharma Grade)

  • Ideal for clarification and prefiltration

  • High consistency for validated analytical methods

✅ No Initial Flush Required (Validated)

  • Extractable-free from first filtrate

  • Eliminates sample waste and variability

Ultra-Low Adsorption

  • Suitable for charged and sensitive analytes

  • Maximizes analyte recovery

Optimized for Low Sample Volumes (13 mm)

  • Minimizes sample loss

  • Efficient for small-volume workflows

Regulatory Compliance

  • Meets FDA CFR Title 21 requirements

  • Complies with USP <788>

  • Suitable for Sterile Water for Injection

Broad Solvent Compatibility

  • Compatible with aqueous and organic HPLC solvents

  • Ideal for mixed solvent systems

Autoclavable & EO Sterilizable

  • 121°C for 30 minutes or Ethylene Oxide

Color-Coded (Green)

  • Identifies 0.45 µm nylon filters


Typical Applications

  • HPLC & UHPLC Sample Preparation – small-volume sample clarification

  • Dissolution Testing – pharmaceutical QC workflows

  • Method Development – limited sample volumes

  • Regulated Laboratory Methods – validated, compliant processes

  • Pharmaceutical Analysis – injectables and formulations

  • Aqueous & Organic Filtration – mixed solvent compatibility


Specifications

  • Filter Type: Syringe Filter (Pharma Grade)

  • Membrane Material: Nylon‑66

  • Pore Size: 0.45 µm

  • Diameter: 13 mm

  • Housing Material: Polypropylene (PP)

  • Color Code: Green (0.45 µm Nylon)

  • Connection Type: Luer Lock / Slip

  • Chemical Compatibility: Aqueous and organic solvents

  • Extractables: None detectable (no flush required)

  • Sterilization: Autoclave or EO

  • Compliance: FDA CFR 21, USP <788>

  • Certification: Certificate of Analysis included

  • Sterility: Non-sterile

  • Pack Size: 50/PK

  • Brand: AQ™


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